Characterization of nucleic acids by nanopore analysis.
نویسندگان
چکیده
Single-stranded DNA and RNA molecules in solution can be driven through a nanoscopic pore by an applied electric field. As each molecule occupies the pore, a characteristic blockade of ionic current is produced. Information about length, composition, structure, and dynamic motion of the molecule can be deduced from modulations of the current blockade.
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عنوان ژورنال:
- Accounts of chemical research
دوره 35 10 شماره
صفحات -
تاریخ انتشار 2002